Global Antibiotic Resistance: A Growing Crisis Antibiotic resistance causes approximately 1.27 million deaths annually worldwide, with projections suggesting 10 million deaths per year by 2050 if current trends continue. The overuse of antibiotics in human medicine and livestock farming—where 73% of global antibiotic sales occur in agriculture—has accelerated the emergence of multidrug-resistant pathogens like MRSA and carbapenem-resistant enterobacteria. Historically, antibiotics discovered in the 1940s-1960s revolutionized medicine, but we've now entered an era where bacteria evolve faster than new drugs are developed; the last major antibiotic class was introduced in 2000. This matters because untreated infections from resistant bacteria could render routine surgeries and cancer treatments lethal, effectively reversing decades of medical progress and destabilizing healthcare systems globally.